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Acylation énantiosélective d'un diol méso : le cis-cyclopentène-2 diol-1,4

✍ Scribed by Lucette Duhamel; Thierry Herman


Book ID
104228780
Publisher
Elsevier Science
Year
1985
Tongue
French
Weight
198 KB
Volume
26
Category
Article
ISSN
0040-4039

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## Abstract During the pancreatin‐catalyzed acetylation of the meso‐diol 1 with 2,2,2‐trichloroethyl acetate (2a) in tetrahydrofuran/tri‐ethylamine, the enantiomeric monoacetates 3a and ent‐3a are formed at nearly equal rates. ent‐3a is rapidly acetylated in a second enzyme‐catalyzed step, forming