The role of the carboxylate ion in model
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Weida Tong; Valerian T. D'Souza
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Article
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1995
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John Wiley and Sons
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English
β 810 KB
## Abstract Two exquisite models of the acylβchymotrypsin intermediate, one designed by Bruice and another by Bender, were studied to elucidate the role of the carboxylate ion in the catalytic triad of serine proteases. However, opposing conclusions were drawn from these studies. Computational chem