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Acylation of 2-Azahetarylacetonitriles with (Acetylthio)acetyl and α-(Acetylthio)propionyl Chlorides. Production of 5-Amino-4-hetarylthiophen-3(2H)-ones.

✍ Scribed by Yu. M. Volovenko; T. A. Volovnenko; A. V. Dobrydnev


Book ID
102008549
Publisher
John Wiley and Sons
Year
2007
Weight
24 KB
Volume
38
Category
Article
ISSN
0931-7597

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Abstract

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Reaction of N,N'-dimethyl-2-nitroethene-
✍ María I. García Trimiño; Arturo Macías Hermán Vélez Cabrera Castro; Arístides Ro 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 German ⚖ 594 KB

The redction of N,N -dimethyl-2-nitroethene-I,l-diamine (8) with cc,j-unsaturdted dcyl ISOthiOCydndteS 9 dffords 3,3-diamino-2-nitroacrylthioamides 10 (Scheme 2) in moderate-to-good yields Cyclization of 10 under acidic conditions gives 1,3-thiazin-4-one derivatives of type 11 Oxiddtive cyclization