Acyl Sulfonamide Anti-Proliferatives: Benzene Substituent Structure−Activity Relationships for a Novel Class of Antitumor Agents
✍ Scribed by Lobb, Karen L.; Hipskind, Philip A.; Aikins, James A.; Alvarez, Enrique; Cheung, Yiu-Yin; Considine, Eileen L.; De Dios, Alfonso; Durst, Gregory L.; Ferritto, Rafael; Grossman, Cora Sue
- Book ID
- 115314877
- Publisher
- American Chemical Society
- Year
- 2004
- Tongue
- English
- Weight
- 173 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0022-2623
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Most of the drugs available today for the treatment of cancer are based on the inhibition of cell proliferation and induction of cell death by apoptosis. At the molecular level, the majority of cytotoxic agents interfere with DNA function. However, a prominent subclass of compounds, including paclit
Most of the drugs available today for the treatment of cancer are based on the inhibition of cell proliferation and induction of cell death by apoptosis. At the molecular level, the majority of cytotoxic agents interfere with DNA function. However, a prominent subclass of compounds, including paclit
**Leistungsstarke Tumortherapeutika** der Epothilon‐Familie wirken durch Bindung an Tubulin und Beeinflussung der Microtubuli‐Entwicklung. Bisher sind keine hochaufgelösten Strukturen von Tubulin‐Epothilon‐Komplexen verfügbar, doch ließen sich NMR‐spektroskopisch zwei größere Konformationsänderungen