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Acute treatment with methotrexate induces hippocampal dysfunction in a mouse model of breast cancer

โœ Scribed by Miyoung Yang; Joong-Sun Kim; Juhwan Kim; Sungwoong Jang; Sung-Ho Kim; Jong-Choon Kim; Taekyun Shin; Hongbing Wang; Changjong Moon


Book ID
116327396
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
615 KB
Volume
89
Category
Article
ISSN
0361-9230

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## Abstract Hepsin is a serine protease that is widely expressed in different tissues and cell types, most prominently in the normal liver and kidney. Overexpression of hepsin has been associated with prostate cancers, ovarian cancers and renal cell carcinomas. The physiological functions of hepsin