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Acute toxicity of perfluorodecanoic acid and cobalt protoporphyrin in a TCDD-sensitive and a TCDD-resistant rat strain

✍ Scribed by Mikko Unkila; Raimo Pohjanvirta; Jouko Tuomisto


Book ID
116079033
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
275 KB
Volume
25
Category
Article
ISSN
0045-6535

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## Abstract An acutely toxic dose of 2,3,7,8‐tetrachlorodibenzo‐__p__‐dioxin (TCDD) leads to a drastically and permanently reduced feed intake and wasting by an unknown mechanism. We focused on the possible interference of TCDD with hypothalamic factors known to take part in the regulation of eatin