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Acute toxicities of the fungicide pentachloronitrobenzene and of some of its sulphur-containing metabolites administered to mice

✍ Scribed by G. Renner; Phuc-Trung Nguyen


Publisher
Springer-Verlag
Year
1982
Tongue
English
Weight
166 KB
Volume
51
Category
Article
ISSN
0340-5761

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Metabolism of the mesoionic compound (MI
✍ Silvia Romão; Silvia M. S. C. Cadena; Juliana C. Amorim; Stelia C. Méndez-Sánche 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 528 KB

## Abstract The mesoionic derivative 4‐phenyl‐5‐[4‐nitrocinnamoyl]‐1,3,4‐thiadiazolyl‐2‐phenylamine chloride (MI‐D) has antitumoral and anti‐inflammatory effects. In this study, we present aspects of its metabolism and toxicity in mice. MI‐D was metabolized __in vitro__ by liver microsome, generati