Acute reversible parkinsonism in Epstein–Bbarr virus–related encephalitis lethargica-like illness
✍ Scribed by Petia S. Dimova; Veneta Bojinova; Dimitar Georgiev; Ivan Milanov
- Book ID
- 102507749
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 81 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0885-3185
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✦ Synopsis
Abstract
A 10‐year‐old boy presented with fever, headache, vomiting, and hypersomnolence. An akinetic–rigid syndrome with tremor, dysphagia, dysphonia, and sialorrhea, as well as pyramidal signs, developed. Slightly elevated protein content was found in the cerebrospinal fluid and serological investigations were suggestive of a primary Epstein–Barr virus infection. Magnetic resonance imaging (MRI) showed massive bilateral hyperintense striatal and punctiform periventricular lesions. After 2‐month treatment with steroids and antiparkinsonian drugs, all features resolved without sequelae. Control MRI demonstrated only minimal residual lesions in both putamina. Strongly resembling the encephalitis lethargica‐like syndrome, this case is an unusual presentation of parainfectious acute disseminated encephalitis. © 2005 Movement Disorder Society