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Acute Renal Failure in Sickle-Cell Disease

✍ Scribed by Kelly, Carolyn J.; Singer, Irwin

Book ID: 124113326
Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 806 KB
Volume: 8
Category: Article
ISSN: 0272-6386
DOI: 10.1016/S0272-6386(86)80017-8

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Sickle cell anemia and the related hemoglobinopathies are associated with a large spectrum of renal abnormalities. The patients have impaired urinary concentrating ability, defects in urinary acidification and potassium excretion, and supranormal proximal tubular function. The latter is manifest by