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Acute pharmacokinetic and hemodynamic effects of intravenous bolus dosing of nicardipine

โœ Scribed by Deanna G. Cheung; Julie L. Gasster; Joel M. Neutel; Michael A. Weber

Book ID
117009181
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
459 KB
Volume
119
Category
Article
ISSN
1097-6744

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Single intravenous dose and steady-state
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โœ John G. Wagner; Teck L. Ling; Edward J. Mroszczak; Donna Freedman; Ann Wu; Bee H ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 617 KB

Nicardipine HCI oral doses (10-40 mg) were administered sequentially to six healthy subjects. For each regimen the capsule dose was administered every 8 hours (q 8 h) for 3 days and the plasma profiles of nicardipine and its pyridine analogue (M5) were determined following the last dose on day 4. St