✦ LIBER ✦

Acute myeloid leukemia harboring t(8;21)(q22;q22): a heterogeneous disease with poor outcome in a subset of patients unrelated to secondary cytogenetic aberrations

✍ Scribed by Lin, Pei; Chen, Lei; Luthra, Rajyalakshmi; Konoplev, Sergej N; Wang, Xuemei; Medeiros, L Jeffrey

Book ID: 109887718
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 151 KB
Volume: 21
Category: Article
ISSN: 0893-3952
DOI: 10.1038/modpathol.2008.92

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Translocation (8;12;21)(q22.1;q24.1;q22.

Translocation (8;12;21)(q22.1;q24.1;q22.1): A New Masked Type of t(8;21)(q22;q22) in a Patient with Acute Myeloid Leukemia

✍ Kohki Saitoh; Ikuo Miura; Atsushi Ohshima; Naoto Takahashi; Masaaki Kume; Seiko 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 274 KB

Complex t(8;13;21)(q22;q14;q22)–A Novel

Complex t(8;13;21)(q22;q14;q22)–A Novel Variant of t(8;21) in a Patient with Acute Myeloid Leukemia (AML–M2)

✍ Achandira Muthappa Udayakumar; Salam Alkindi; Anil Vasanth Pathare; John Alexand 📂 Article 📅 2008 🏛 Elsevier Science 🌐 English ⚖ 393 KB

Good outcome of children with acute myel

Good outcome of children with acute myeloid leukemia and t(8;21)(q22;q22), even when associated with granulocytic sarcoma : A report from a single institution in Argentina

✍ María S. Felice; Pedro A. Zubizarreta; Elizabeth M. Alfaro; Marta S. Gallego; An 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 83 KB 👁 1 views

## BACKGROUND. The association between t(8;21) and granulocytic sarcoma (GS) is well known, but to the authors' knowledge the prognostic significance of GS in these patients has not been defined clearly. ## METHODS. Between January 1990 and July 1999 174 children with acute myeloid leukemia were

LPXN, a member of the paxillin superfami

LPXN, a member of the paxillin superfamily, is fused to RUNX1 in an acute myeloid leukemia patient with a t(11;21)(q12;q22) translocation

✍ Hai-Ping Dai; Yong-Quan Xue; Jian-Wei Zhou; Ai-Ping Li; Ya-Fang Wu; Jin-Lan Pan; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 342 KB 👁 1 views

## Abstract __RUNX1__ (previously __AML1__) is involved in multiple recurrent chromosomal rearrangements in hematological malignances. Recently, we identified a novel fusion between __RUNX1__ and __LPXN__ from an acute myeloid leukemia (AML) patient with t(11;21)(q12;q22). This translocation genera

PRDX4, a member of the peroxiredoxin fam

PRDX4, a member of the peroxiredoxin family, is fused to AML1 (RUNX1) in an acute myeloid leukemia patient with a t(X;21)(p22;q22)

✍ Yanming Zhang; Neelmini Emmanuel; Ginny Kamboj; Jianjun Chen; Muhammad Shurafa; 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 210 KB 👁 1 views

## Abstract The __AML1__ gene (also known as __RUNX1__) at 21q22 codes for core binding factor (CBF) α, which forms a heterodimer with CBF β that acts as a transcriptional activating factor. CBF is a critical regulator in the generation and differentiation of definitive hematopoietic stem cells and