## Abstract An infant with Down syndrome (DS) and RH isoimmunization developed transient myeloproliferative disorder (TMD) during the neonatal period. At 16 months she presented with acute nonlymphocytic leukemia (ANLL). Cytogenetic studies during TMD showed trisomy 21 only but new abnormalities em
Acute megakaryoblastic leukemia following transient myeloproliferative disorder in a patient without down syndrome
β Scribed by Mark D. Brissette; Bertrand J. Duval-Arnould; Bruce G. Gordon; Dr. James D. Cotelingam
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 677 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0361-8609
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## Abstract We report the serial cytogenetic study of a patient with Down syndrome who experienced a congenital leukemoid reaction, underwent a spontaneous remission within four months, and subsequently developed acute myeloid leukemia at 16 months. A blood chromosome study to rule out Down syndrom
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