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Acute lymphoblastic leukemia in a patient with chronic granulomatous disease and a novel mutation in CYBB: First report

✍ Scribed by Baruch Wolach; Shifra Ash; Ronit Gavrieli; Batia Stark; Isaac Yaniv; Dirk Roos


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
168 KB
Volume
80
Category
Article
ISSN
0361-8609

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The authors describe a family with two children with microcephaly and normal intelligence, in which acute lymphoblastic leukemia developed in one of the siblings. An autosomal recessive pattern of inheritance is suggested by the pedigree. This is consistent with the literature, which the authors rev