Acute leukemia: Diagnosis improved by flow cytometry in addition to morphology
โ Scribed by Manju SENGAR; Ambak K RAI; Ankit SAXENA; Amar SINGH; Vinod RAINA; Tulika SETH; Atul SHARMA; Sameer BAKHSI; Rajive KUMAR; Dipendra K MITRA
- Book ID
- 111318728
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 343 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1743-7555
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The value of flow cytometric detection of myeloperoxidase (MPO) in the differential diagnosis of acute leukemia was evaluated in 57 cases of acute leukemia and in 9 leukemia cell lines. Cells were fixed and permeabilized with Fix & Perm cell permeabilization kit at room temperature for 15 min each,
Patients with acute leukemia in clinical remission may still have up to 10 10 residual malignant cells (the upper limit of detection by standard morphologic techniques). Sensitive techniques to detect minimal residual disease (MRD) may allow better estimates of the leukemia burden and help the selec