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Acute kinetic and dynamic interactions of zimelidine with ethanol

✍ Scribed by Naranjo, Claudio A; Sellers, Edward M; Kaplan, Howard L; Hamilton, Carolyn; Khouw, Virginia

Book ID
109843490
Publisher
Nature Publishing Group
Year
1984
Tongue
English
Weight
415 KB
Volume
36
Category
Article
ISSN
0009-9236

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Six healthy male volunteers took part in this three-period crossover study. In each session, a dose of trial drug -- either placebo, zimelidine 200 mg, or amitriptyline 75 mg -- was given at 09.00 h. Ethanol (50 g) was taken orally at 1200 h. Blood samples were taken for measurement of drug and etha