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Acute intermittent porphyria with transient cortical blindness

✍ Scribed by Javeed Iqbal Bhat; Umar Amin Qureeshi; Mushtaq Ahmad Bhat


Book ID
107697627
Publisher
Indian Academy of Pediatrics
Year
2010
Tongue
English
Weight
394 KB
Volume
47
Category
Article
ISSN
0019-6061

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Diminished activity of uroporphyrinogen I-synthetase in the liver and other tissues may be regarded to be the primary genetic deficiency of acute intermittent porphyria (AIP). Increased production and renal excretion of delta-aminolevulinic acid (ALA) und porphobilinogen (PBG) are secondary phenomen