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Acute in vivo effects of insulin on gene expression in adipose tissue in insulin-resistant and insulin-sensitive subjects

✍ Scribed by J. Westerbacka; A. Cornér; K. Kannisto; M. Kolak; J. Makkonen; E. Korsheninnikova; T. Nyman; A. Hamsten; R. M. Fisher; H. Yki-Järvinen

Publisher
Springer
Year
2005
Tongue
English
Weight
275 KB
Volume
49
Category
Article
ISSN
0012-186X

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In skeletal muscle, a defect in the covalent activation of glycogen synthase by insulin has been identified in insulin resistance and in Type 2 (non-insulin-dependent) diabetes mellitus, but a similar defect in insulin action at the adipose tissue has not been demonstrated. We sought to determine wh