Acute fatty liver of pregnancy
β Scribed by Khalid Mjahed; Boubker Charra; Driss Hamoudi; Mohamed Noun; Lhoucine Barrou
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 234 KB
- Volume
- 274
- Category
- Article
- ISSN
- 0003-9128
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π SIMILAR VOLUMES
## Abstract Acute fatty liver of pregnancy (AFLP) is a rare disease of progressive hepatic insufficiency and secondary systemic compromise that poses significant fetalβmaternal risk. Plasma exchange (PEX) is an effective bridge therapy to sustain liver function and enable hepatocellular regeneratio
A previously healthy 35-year-old woman was seen at 37 weeks' gestation with a 10-day history of fever, vomiting, diarrhea and malaise. Serum laboratory findings included elevation of serum bilirubin and AST, prolongation of serum prothrombin time and a positive monospot. A tentative diagnosis of acu
The pathogenesis of acute fatty liver of pregnancy is unknown, but similarities in the clinical presentation and the histological appearance of the liver with those found in children with metabolic defects in the intramitochondrial fboxidation pathway of the liver suggest that a disturbance in hepat