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Acute exercise reverses TRB3 expression in the skeletal muscle and ameliorates whole body insulin sensitivity in diabetic mice

โœ Scribed by A. Matos; E. R. Ropelle; J. R. Pauli; M. J. S. Frederico; R. A. De Pinho; L. A. Velloso; C. T. De Souza


Book ID
111383927
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
287 KB
Volume
198
Category
Article
ISSN
1748-1708

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Acute exercise reduces insulin resistanc
โœ Athos F. Lima; Eduardo R. Ropelle; Josรฉ R. Pauli; Dennys E. Cintra; Marisa J.S. ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 182 KB

## Abstract TRB3 (a mammalian homolog of __Drosophila__) is emerging as an important player in the regulation of insulin signaling. TRB3 can directly bind to Ser/Thr protein kinase Akt, the major downstream kinase of insulin signaling. Conversely, physical exercise has been linked to improved gluco