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Acute Exacerbation of Chronic Hepatitis B Virus Infection After Withdrawal of Lamivudine Therapy

โœ Scribed by Pieter Honkoop; Robert A. de Man; Hubert G.M. Niesters; Pieter E. Zondervan; Solko W. Schalm

Book ID
111721128
Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
141 KB
Volume
32
Category
Article
ISSN
0270-9139

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โœ Yun-Fan Liaw; Rong-Nan Chien; Chau-Ting Yeh; Sun-Lung Tsai; Chia-Ming Chu ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 77 KB ๐Ÿ‘ 1 views

Lamivudine is a potent inhibitor of hepatitis B virus (HBV) replication, but its long-term use may be associated with HBV tyrosine-methionine-aspartate-aspartate (YMDD) motif mutation. To examine the clinical features and course after emergence of YMDD mutants, 55 patients who received lamivudine th