We report a case of homozygous alpha-thalassaemia with hydrops fetalis presenting at 22 weeks of gestation. In utero exchange transfusion was performed with maternal blood at 23 weeks. 25 weeks and 29 weeks of gestation. The fetus was delivered at 29 weeks of gestation without significant neonatal c
Acute cerebrovascular insults in homozygous beta-thalassaemia: a case report
โ Scribed by E. Paolino; V. C. Monetti; E. Granieri; P. Boldrini
- Book ID
- 104717886
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 281 KB
- Volume
- 230
- Category
- Article
- ISSN
- 0340-5354
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โฆ Synopsis
Neurological complications following vascular thrombotic crises are frequent and occur in sickle cell anaemia and its variants, but are less well recognized in thalassaemias. A case of beta-thalassaemia major is reported complicated by an ischaemic lesion involving the right cerebellar hemisphere. The probable pathogenesis is considered and the literature on the matter briefly reviewed. In agreement with other reports, the interference of risk factors provided by or occurring in association with multiple blood-transfusions is hypothesized. Consequently, caution is recommended in giving large blood-transfusions to thalassaemic patients.
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