✦ LIBER ✦

Acute ataxia, Graves' disease, and stiff person syndrome

✍ Scribed by Su-Ynn Chia; Richard Chua; Yew-Long Lo; Meng-Cheong Wong; Ling-Ling Chan; Eng-King Tan

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 56 KB
Volume: 22
Category: Article
ISSN: 0885-3185
DOI: 10.1002/mds.21703

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✦ Synopsis

Abstract

Stiff person syndrome (SPS) has been associated with autoimmune diseases, such as Type 1 diabetes mellitus and autoimmune thyroid disease (Hashimoto's thyroiditis), among others. The association of SPS with hyperthyroidism is extremely rare. We describe a patient with uncontrolled Graves' disease and undiagnosed SPS, who presented initially with acute ataxia simulating a cerebrovascular accident. Initiation of immunosuppressive therapy dramatically improved the patient's Graves' disease within 2 weeks but the neurological symptoms were not alleviated after a follow‐up period of 3 years. © 2007 Movement Disorder Society

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