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Acute and sub-chronic oral toxicological evaluations of quinocetone in Wistar rats

โœ Scribed by Xu Wang; Wei Zhang; Yulian Wang; Dapeng Peng; Awais Ihsan; Xianju Huang; Lingli Huang; Zhenli Liu; Menghong Dai; Wen Zhou; Zong-Hui Yuan


Book ID
113965629
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
635 KB
Volume
58
Category
Article
ISSN
0273-2300

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Sub-acute versus sub-chronic oral toxici
โœ Rund A. Woutersen; Heero P. Til; Victor J. Feron ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 376 KB

Toxicity data of 82 compounds, tested in both B sub-acute and a sub-chronic study, were evaluated to find out whether it is possible to substitute a sub-acute for a sub-chronic study without losing quantitative information. The no-effect level (NEL) and the minimal-effect level (MEL) were used as th