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Acute and chronic effects of aluminum on acetyl-CoA and acetylcholine metabolism in differentiated and nondifferentiated SN56 cholinergic cells

✍ Scribed by Agnieszka Jankowska; Beata Madziar; Maria Tomaszewicz; Andrzej Szutowicz

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 153 KB
Volume: 62
Category: Article
ISSN: 0360-4012
DOI: 10.1002/1097-4547(20001115)62:4<615::aid-jnr17>3.0.co;2-1

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Acetylcholine and acetyl-CoA metabolism

Acetylcholine and acetyl-CoA metabolism in differentiating SN56 septal cell line

✍ Andrzej Szutowicz; Agnieszka Jankowska; Jan K. Blusztajn; Maria Tomaszewicz 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 143 KB

The rate of acetylcholine (ACh) synthesis was found to depend on the activity of choline acetyltransferase (ChAT) and on the concentrations of the two substrates of this enzyme, choline and acetyl-CoA. In SN56 cells treated for 3 days with 1 mM dbcAMP activities of ChAT and acetylcholinesterase (ACh