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Acute and chronic amphetamine treatments modulate striatal dopamine receptor binding sites

โœ Scribed by D.R. Howlett; S.R. Nahorski


Book ID
118864890
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
329 KB
Volume
161
Category
Article
ISSN
0006-8993

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## Abstract We studied the in vitro electrical activity of rat neostriatal neurons following chronic neuroleptic treatment. In haloperidolโ€treated rats, unlike naive animals, activation of neostriatal D2 dopamine receptors induced a potent presynaptic inhibition of glutamateโ€mediated excitatory syn