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Acute and chronic administration of diphenylhydantoin (DPH) in rats: Behavioural effects

✍ Scribed by R. Cagiano; I. Cortese; M.A. De Salvia; G. Renna; E. Tortella; V. Lepore; V. Cuomo

Book ID
114075486
Publisher
Elsevier Science
Year
1988
Weight
76 KB
Volume
20
Category
Article
ISSN
0031-6989

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An original parent group of 72 Sprague-Dawley albino rats was subdivided into four treatment groups that were administered 5, 10 or 15 mg/kg diphenylhydantoin and distilled water on days 5 to 55 after birth. At 85 days of age the drug females were bred to naive males to produce an F1 generation. In