Kynurenic acid synthesis in cerebral cor
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Tomasz Saran; Wojciech Hilgier; Ewa M. UrbaΕska; Waldemar A. Turski; Jan Albrech
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Article
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2004
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John Wiley and Sons
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English
β 131 KB
## Abstract Increased ammonia is a major pathogenic factor in hepatic encephalopathy (HE), a neurologic syndrome associated with glutamatergic dysfunction. Previous studies have shown that in rat cerebral cortical slices or a gliaβderived cell line, acute treatment with ammonia in vitro and in vivo