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Acute 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure Results in Enhanced Tyrosylphosphorylation and Expression of Murine Hepatic Cyclin Dependent Kinases

✍ Scribed by X.F. Ma; J.G. Babish


Book ID
115573958
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
362 KB
Volume
197
Category
Article
ISSN
0006-291X

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## Abstract The cytochrome P450 (CYP) isoform CYP2C11 is specifically expressed in the liver of adult male rats, and 5α‐reductase is specifically expressed in the liver of the adult female rats. The sexually dimorphic expressions of these hepatic enzymes are regulated by the sex‐dependent profiles