Melatonin protects hippocampal neurons i
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Dun-xian Tan; Lucien C. Manchester; Russel J. Reiter; Wenbo Qi; Seok Joong Kim;
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Article
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1998
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John Wiley and Sons
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English
⚖ 257 KB
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In this investigation, 40 mg/kg of the excitatory neurotoxin kainic acid (KA) was subcutaneously administered to CD2-F1 mice. In this mouse strain morphological damage induced by KA in the hippocampus was markedly concentrated in the CA3 pyramidal neurons. Neuronal injury was accompanied by several