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Activity of urethane and N,N-dimethylurethane in the mouse bone-marrow micronucleus assay: Equivalence of oral and intraperitoneal routes of exposure

โœ Scribed by J. Ashby; H. Tinwell; R.D. Callander


Book ID
113255356
Publisher
Elsevier Science
Year
1990
Weight
246 KB
Volume
245
Category
Article
ISSN
0165-7992

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The genetic activity of the structurally similar antitumor antibiotics anthramycin, tomaymycin and sibiromycin was evaluated in the standard Ames Salmonella/microsome mutagenicity assay, a Salmonella typhimun'um forward-mutation assay and the micronucleus test. None of the test drugs showed any sign