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Activity of trabectedin (ET-743, Yondelis) in metastatic uterine leiomyosarcoma

✍ Scribed by Devansu Tewari; Bahman Saffari; Carol Cowan; Anita C. Wallick; M. Zach Koontz; Bradley J. Monk

Book ID: 113960636
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 684 KB
Volume: 102
Category: Article
ISSN: 0090-8258
DOI: 10.1016/j.ygyno.2006.04.025

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## Abstract The development of a simple and sensitive assay for the quantitative analysis of the marine anticancer agent Yondelis (ET‐743, trabectedin) in human plasma using liquid chromatography (LC) with column switching and tandem mass spectrometric (MS/MS) detection is described. After protein