✦ LIBER ✦

Activity of the mTOR inhibitor RAD001, the dual mTOR and PI3-kinase inhibitor BEZ235 and the PI3-kinase inhibitor BKM120 in hepatocellular carcinoma

✍ Scribed by Kirstein, Martha M.; Boukouris, Aristeidis E.; Pothiraju, Deepika; Buitrago-Molina, Laura E.; Marhenke, Silke; Schütt, Jutta; Orlik, Johanna; Kühnel, Florian; Hegermann, Jan; Manns, Michael P.; Vogel, Arndt

Book ID: 120137426
Publisher: John Wiley and Sons
Year: 2013
Tongue: English
Weight: 875 KB
Volume: 33
Category: Article
ISSN: 0106-9543
DOI: 10.1111/liv.12126

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

1057 ANTI-TUMOR ACTIVITY OF THE mTOR INH

1057 ANTI-TUMOR ACTIVITY OF THE mTOR INHIBITOR RAD001, THE DUAL mTOR/PI3-KINASE INHIBITOR BEZ235 AND THE PI3-KINASE INHIBITOR BKM120 CORRELATES WITH IMPAIRMENT OF OXIDATIVE PHOSPHORYLATION IN HCC

✍ Kirstein, M.M.; Boukouris, A.E.; Pothiraju, D.; Buitrago-Molina, L.E.; Marhenke, 📂 Article 📅 2013 🏛 Elsevier Science 🌐 English ⚖ 53 KB

369 Effects of the Specific PI3K Inhibit

369 Effects of the Specific PI3K Inhibitor BKM120, the Dual PI3K/mTOR Inhibitor BEZ235, and Specific mTOR Inhibitors Everolimus and Temsirolimus in Renal and Hepatic Carcinoma Models Resistant to Sunitinib and Sorafenib

✍ Serova, M.; Raballand, A.; Dos Santos, C.; Riveiro, E.; Raymond, E.; Faivre, S.; 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 58 KB

Efficacy of the novel dual PI3-kinase/mT

Efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 in a preclinical model of adrenocortical carcinoma

✍ Doghman, Mabrouka; Lalli, Enzo 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 535 KB

Activity of a novel, dual PI3-kinase/mTo

Activity of a novel, dual PI3-kinase/mTor inhibitor NVP-BEZ235 against primary human pancreatic cancers grown as orthotopic xenografts

✍ Cao, P; Maira, S-M; García-Echeverría, C; Hedley, D W 📂 Article 📅 2009 🏛 Nature Publishing Group 🌐 English ⚖ 487 KB

The PI3 kinase/mTOR blocker NVP-BEZ235 o

The PI3 kinase/mTOR blocker NVP-BEZ235 overrides resistance against irreversible ErbB inhibitors in breast cancer cells

✍ Caroline Brünner-Kubath; Waheed Shabbir; Victoria Saferding; Renate Wagner; Chri 📂 Article 📅 2010 🏛 Springer US 🌐 English ⚖ 756 KB

NVP-BEZ235, a dual pan class I PI3 kinas

NVP-BEZ235, a dual pan class I PI3 kinase and mTOR inhibitor, promotes osteogenic differentiation in human mesenchymal stromal cells

✍ Sally K Martin; Stephen Fitter; Li Fei Bong; Jennifer J Drew; Stan Gronthos; Pet 📂 Article 📅 2010 🏛 American Society for Bone and Mineral Research 🌐 English ⚖ 523 KB

## Abstract Osteoblasts are bone‐forming cells derived from mesenchymal stromal cells (MSCs) that reside within the bone marrow. In response to a variety of factors, MSCs proliferate and differentiate into mature, functional osteoblasts. Several studies have shown previously that suppression of the