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Activity of nitro-polynuclear aromatic hydrocarbons in the sister chromatid exchange assay with and without metabolic activation

✍ Scribed by Nachtman, Joseph P. ;Wolff, Sheldon

Publisher
Wiley (John Wiley & Sons)
Year
1982
Weight
321 KB
Volume
4
Category
Article
ISSN
0192-2521

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## Abstract The frequency of sister chromatid exchange (SCE) in WI‐38 cells was estimated by the 5‐bromodeoxyuridine (BrdUrd)‐dye technique after one hour's exposure to cyclophosphamide (CY), N‐methyl‐N′‐nitro‐N‐nitrosoguanidine (MNNG), 4‐nitroquinoline‐1‐oxide (4NQO), and maleic hydrazide (MH) wit