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Activity of CYP2E1 measured by the chlorzoxazone test in patients with non-alcoholic steatohepatitis and activation of stellate cells

✍ Scribed by David Semela; Monika Ledermann; Arthur Zimmermann; Jean-Francois Dufour


Book ID
118565442
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
108 KB
Volume
36
Category
Article
ISSN
0168-8278

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Assessment of ifosfamide pharmacokinetic
✍ Rashmi Chugh; Thomas Wagner; Kent A. Griffith; Jeremy M.G. Taylor; Dafydd G. Tho πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 190 KB

## Abstract ## BACKGROUND. Ifosfamide is a chemotherapeutic agent that requires cytochrome P450 3A (CYP3A) for bioactivation and metabolism. To the authors' knowledge, the correlation between dose, pharmacokinetics, CYP3A, and toxicity has not been fully evaluated. A randomized Phase II trial was