Activity of chondroitin ABC lyase on dermatan sulfate partially degraded by cupric-ion-mediated free-radical treatment

Activity of chondroitin ABC lyase and hy

Activity of chondroitin ABC lyase and hyaluronidase on free-radical degraded chondroitin sulfate

✍ Nicola Volpi; Ilaria Sandri; Tiziana Venturelli 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 636 KB

High molecular mass-chondroitin sulfate was characterized for M(r), charge density and constituent disaccharides. This glycosaminoglycan was depolymerized by a controlled free-radical process mediated by hydrogen peroxide in the absence or presence of cupric or ferrous ions. Hydrogen peroxide depoly