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Activity-dependent survival and enhanced turnover of calcium in cultured rat cerebellar granule neurons

✍ Scribed by Keigo Kohara; Tomio Ono; Keiko Tominaga-Yoshino; Tomokazu Shimonaga; Seiichi Kawashima; Akihiko Ogura

Book ID
114004326
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
416 KB
Volume
809
Category
Article
ISSN
0006-8993

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In order to investigate the molecular mechanism underlying synaptogenesis, we examined the dynamics and stability of syntaxin 1A and SNAP-25 in cultured cerebellar granule cells. In neurons cultured for less than 5 days in vitro (DIV), syntaxin was highly expressed with a half-life of ΟΎ48 hours. SNA