Activity-based anorexia during adolescence does not promote binge eating during adulthood in female rats
✍ Scribed by Cai, Wenli ;Bocarsly, Miriam E. ;Arner, Candice N. ;Walsh, B. Timothy ;Foltin, Richard W. ;Hoebel, Bartley G. ;Barbarich-Marsteller, Nicole C.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2008
- Tongue
- English
- Weight
- 95 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0276-3478
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Objective:
Given the frequency of transition from anorexia nervosa to bulimia nervosa, this study investigated whether a history of activity‐based anorexia (ABA) during adolescence would promote binge eating during adulthood in female rats.
Method:
Adolescent rats were given 1‐h unlimited access to chow and ad libitum access to a running wheel until body weight reached <80%, indicating the development of ABA. During adulthood, all groups were given 21 days of access to a palatable food for 2 h/day and ad libitum access to chow.
Results:
During adolescence, rats in the ABA paradigm developed increased wheel running and decreased food intake, reaching <80% of body weight after 3 days. However, there were no significant differences between groups in the amount of binge food consumed during adulthood.
Conclusion:
A brief episode of ABA during adolescence did not lead to increased binge eating later in life. Longer‐term models are needed to determine whether a propensity toward binge eating may result from more sustained ABA during adolescence. © 2008 by Wiley Periodicals, Inc. Int J Eat Disord 2008