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Activity and Stoichiometry of Na+:HCO−3Cotransport in Immortalized Renal Proximal Tubule Cells

✍ Scribed by E. Gross; U. Hopfer

Publisher
Springer
Year
1996
Tongue
English
Weight
179 KB
Volume
152
Category
Article
ISSN
0022-2631

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✍ Sónia Simão; Pedro Gomes; Maria João Pinho; Patrício Soares-da-Silva 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 268 KB

Cl(-) /HCO (3)(-) exchanger and Na(+) /H(+) exchanger 3 are the main transporters responsible for NaCl reabsorption in kidney proximal tubules (PT). It is well accepted that membrane exchangers can be regulated by reactive oxygen species (ROS). In the kidney, ROS are known to contribute to decreases