Activity and expression of ecto-nucleotide pyrophosphate/phosphodiesterases in a hepatic stellate cell line
✍ Scribed by Cláudia M. B. Andrade; Márcia R. Wink; Rogério Margis; Radovan Borojevic; Ana Maria O. Battastini; Fátima C. R. Guma
- Book ID
- 106458789
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 266 KB
- Volume
- 325
- Category
- Article
- ISSN
- 0300-8177
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## Activation of local tissue macrophages (Kupffer cells) and of quiescent hepatic stellate cells (HSCs ) to a myofibroblast phenotype are two key events in liver inflammation and fibrosis. It is known that products of activated macrophages may activate stellate cells. We have hypothesized that th