β Scribed by Radany, Eric H. ;Nguyen, Hong T. ;Minton, Kenneth W.
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Endogenous oxidative damage to brain mitochondrial DNA and consequential disturbances of gene expression and mitochondrial dysfunction have long been implicated in aging and the pathogenesis of neurodegenerative diseases. It has yet to be determined, however, whether mitochondria in brain cells cont
The OGG1 gene of Saccharomyces cerevisiae encodes a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine (8-OxoG). When compared to wild-type, ogg1 mutants show an increase in the frequency of GC to TA transversions, indicating a role for Ogg1 in the repair of 8-OxoG. Here we report an increased fr
## Abstract ## BACKGROUND. Tobacco smoke contains numerous carcinogens that cause DNA damage, including oxidative lesions that are removed effectively by the baseβexcision repair (BER) pathway, in which adenosine diphosphate ribosyl transferase (ADPRT), xβray repair crossβcomplementing 1 (XRCC1),