Active two-channel 0.035″ guidewire for interventional cardiovascular MRI
✍ Scribed by Ozgur Kocaturk; Ann H. Kim; Christina E. Saikus; Michael A. Guttman; Anthony Z. Faranesh; Cengizhan Ozturk; Robert J. Lederman
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 439 KB
- Volume
- 30
- Category
- Article
- ISSN
- 1053-1807
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✦ Synopsis
Abstract
Purpose
To develop an “active” (receiver‐coil) clinical‐grade guidewire with enhanced visibility for magnetic resonance imaging (MRI) and favorable mechanical characteristics for interventional MRI procedures that require conspicuous intravascular instruments distinguishable from surrounding tissues.
Materials and Methods
We designed a 0.035‐inch guidewire combining two antenna designs on separate channels. A loop antenna visualizes the tip and a dipole antenna visualizes the whole shaft. We compared mechanical characteristics of this guidewire with x‐ray alternatives and tested MRI performance at 1.5T in vitro and in vivo in swine.
Results
Images reflected tip position within 0.97 ± 0.42 mm and afforded whole‐shaft visibility under expected conditions without sacrificing device size or handling. We report tip stiffness, torquability, and pushability comparable to commercial interventional guidewires.
Conclusion
Our clinical‐grade 0.035‐inch active guidewire is conspicuous under MRI and has mechanical performance comparable to x‐ray interventional guidewires. This may enable a range of interventional procedures using real‐time MRI. J. Magn. Reson. Imaging 2009;30:461–465. © 2009 Wiley‐Liss, Inc.