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Active site mutant acetylcholinesterase interactions with 2-PAM, HI-6, and DDVP

✍ Scribed by Zrinka Kovarik; Nikolina Ciban; Zoran Radić; Vera Simeon-Rudolf; Palmer Taylor


Book ID
116292428
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
169 KB
Volume
342
Category
Article
ISSN
0006-291X

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Synthesis of tritium labelled oximes: 2-
✍ Ayala Balan; Itzhak Barness; Gabriel Amitai 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 French ⚖ 441 KB

## Abstract Synthesis of two quaternary pyridinium oximes [^3^H]2‐PAM and [^3^H]HI‐6 (18 and 22 Ci/mmole, respectively) was performed by using unlabelled 6‐bromo 2‐pyridine aldehyde (I) as a common starting material. The labelling was based on a catalytic ring‐tritiation of 6‐bromo 2‐diethylketal p