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Active site analysis ofcis-epoxysuccinate hydrolase fromNocardia tartaricansusing homology modeling and site-directed mutagenesis

✍ Scribed by Vinayagam Vasu; Jayaraman Kumaresan; Manoharan Ganesh Babu; Sankaranarayanan Meenakshisundaram


Publisher
Springer
Year
2011
Tongue
English
Weight
545 KB
Volume
93
Category
Article
ISSN
1432-0614

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Protein C (PC) is activated to an essential anticoagulant enzyme (activated PC or APC) by thrombin (T) bound to thrombomodulin (TM), a membrane receptor present on the surface of endothelial cells. The understanding of this complex biological system is in part limited due to the lack of integration