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Active immunization of metastatic melanoma patients with interleukin-2-transduced allogeneic melanoma cells: evaluation of efficacy and tolerability

✍ Scribed by Filiberto Belli; Flavio Arienti; J. Sulé-Suso; C. Clemente; Luigi Mascheroni; Alessandro Cattelan; Cristina Santantonio; Gian Francesco Gallino; Cecilia Melani; Stefania Rao; Mario P. Colombo; Michele Maio; Natale Cascinelli; G. Parmiani

Book ID
105968204
Publisher
Springer-Verlag
Year
1997
Tongue
English
Weight
943 KB
Volume
44
Category
Article
ISSN
0340-7004

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✍ Sewa S. Legha; Mary Ann Gianan; Carl Plager; Omar E. Eton; Nicholas E. J. Papado 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 726 KB

## BACKGROUND. Interleukin-2 (IL-2) has been used widely in the treatment of advanced melanoma, most often using a high dose bolus schedule of administration. We have evaluated the antitumor activity and toxicity of IL-2 when administered by a continuous infusion schedule in patients with metastat