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Active idiotypic vaccination in a patient with biclonal follicular lymphoma

✍ Scribed by Yvelise Barrios; Aresio Plaza; Rafael Cabrera; Rosa Yáñez; Eduardo Suárez; Manuel Nicolás Fernández; Fernando Díaz-Espada


Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
186 KB
Volume
50
Category
Article
ISSN
0340-7004

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A 39-year-old male with follicular non-Hodgkin's lymphoma was repeatedly studied with respect to D N A rearrangements with the two probes pFL-I and pFL-2, representing two segments of chromosome 18. The oncogene BCL2, detected by pFL-I, was as expected translocated to the J region of the immunoglobu