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Active Efflux Influences the Potency of Quorum Sensing Inhibitors in Pseudomonas aeruginosa

โœ Scribed by Moore, Joseph D.; Gerdt, Joseph P.; Eibergen, Nora R.; Blackwell, Helen E.


Book ID
121862631
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
399 KB
Volume
15
Category
Article
ISSN
1439-4227

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The objective of this study was to screen for novel quorum-sensing inhibitors (QSIs) from traditional Chinese medicines (TCMs) that inhibit bacterial biofilm formation. Six of 46 active components found in TCMs were identified as putative QSIs based on molecular docking studies. Of these, three comp