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Activation of transcription by two factors that bind promoter and enhancer sequences of the human metallothionein gene and SV40

✍ Scribed by Lee, Wes; Haslinger, Alois; Karin, Michael; Tjian, Robert


Book ID
109748185
Publisher
Nature Publishing Group
Year
1987
Tongue
English
Weight
695 KB
Volume
325
Category
Article
ISSN
0028-0836

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Both the mouse and human ␣2(I) procollagen promoters contain an inverted CCAAT box at Οͺ80, but only the human promoter contains an additional regulatory element, the collagen modulating element (CME), immediately downstream of the CCAAT box [Collins et al. (1997): Biochem J 322:199-206]. In this stu