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Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6J-APCMin/+ mice

✍ Scribed by Lefebvre, Anne-Marie; Chen, Inhua; Desreumaux, Pierre; Najib, Jamila; Fruchart, Jean-Charles; Geboes, Karel; Briggs, Mike; Heyman, Rich; Auwerx, Johan


Book ID
109637866
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
298 KB
Volume
4
Category
Article
ISSN
1078-8956

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Peroxisome proliferator-activated recept
✍ Kan Yang; Kun-Hua Fan; Sergio A. Lamprecht; Winfried Edelmann; Levy Kopelovich; 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 201 KB

## Abstract The role of the nuclear peroxisome proliferator‐activated receptor‐γ (PPAR‐γ) in colon tumorigenesis remains controversial. Notwithstanding evidence that PPAR‐γ ligands impede murine colorectal carcinogenesis, PPAR‐γ agonists have been shown to enhance __in vivo__ tumor formation in mou