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Activation of the NF-κB signalling pathway in diffuse large B-cell lymphoma: clinical implications

✍ Scribed by I Espinosa; J Briones; R Bordes; S Brunet; R Martino; A Sureda; J Sierra; J Prat

Book ID
108780618
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
1011 KB
Volume
53
Category
Article
ISSN
0309-0167

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## Abstract Diffuse large B‐cell lymphoma (DLBCL) is an aggressive malignancy with a variable response to therapy. We have previously shown that DLBCL cell lines differ in their susceptibility to CD40‐mediated cell death, and that resistance to CD40‐targeted antibodies correlated with increased exp