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Activation of the mitochondrial caspase cascade in the absence of protein synthesis does not require c-Jun N-terminal kinase

✍ Scribed by Nobuo Watanabe; Takeo Iwamoto; Dale A Dickinson; Karen E Iles; Henry Jay Forman

Book ID: 117042184
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 443 KB
Volume: 405
Category: Article
ISSN: 0003-9861
DOI: 10.1016/s0003-9861(02)00399-5

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## Abstract The roles of the mitogen‐activated kinase protein (MAPK) pathway, nuclear factor‐kappa B (NF‐κB), and activator protein‐1 (AP‐1) in cellular responses to growth factors and mitogen are well established. However, the manner by which these proliferative pathways are affected by the tumor